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KMID : 1100220040030020065
Dementia and Neurocognitive Disorders
2004 Volume.3 No. 2 p.65 ~ p.72
Mechanism of Memory and Disorders of Memory
Yang Dong-Won

Abstract
Among the cognitive processes, the ability to acquire and retain information about the world around us and our experience is vital for the survival of human. This ability, i.e., learning and memory, is mediated by multiple cognitive and neural systems. The hypothetical stages of memory are divided in several steps such as registration, encoding, storage, access, and retrieval. For the good memory, every steps of memory process should be performed successfully. There are several subtypes of memory systems like working memory, semantic memory, episodic memory, as well as memory for skills and procedures. Anatomical structures that are important in memory are different according to the subtypes of memory systems. The medial temporal lobe, thalamic structures and their connections are important for the episodic memory. The frontal lobe is associated with the working memory and the lateral temporal cortex is associated with the semantic memory. Basal ganglia and cerebellum are associated with procedural memory. Many disorders leading to amnesia can affect different structures of brain and cause different patterns of memory dysfunctions. This review helps clinicians and researchers to know the systems and biological structures of memory and to understand the variable clinical features of the amnestic patients.
KEYWORD
Memory, Learning, Episodic, Semantic, Working
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